Posts tagged: ginger

Health Benefits Of Ginger

Health Benefits Of Ginger
Graphic © herbshealthhappiness.com

Ever since ancient times, our ancestors used ginger for medicinal purposes as well as culinary. In more modern times, researchers found that ginger contains a variety of compounds with anti-inflammatory, antioxidative, antimicrobial, and immune-boosting properties.

Studies show that it may reduce inflammation in the body and prevent the accumulation of free radicals. [1] Consequently, ginger has the potential to prevent a myriad of adverse health effects when consumed adequately.

The list of health benefits claimed for ginger is extremely long; additionally, researchers keep unveiling new potential with every new study. Here are the reported benefits of including ginger in your diet: [2]

• Freshens your breath
• Prevents low-grade inflammation and oxidative stress
• Reduces the risk of several types of cancer
• Optimizes the function of the immune system
• Regulates the symptoms of motion seasickness
• Relieves nausea and vomiting
• Improves symptoms of menstrual pain
• Shortens the duration of the common cold and the flu
• Improves food digestion and prevents symptoms of bloating, gas, and abdominal cramping
• Relieves pain caused by headaches and migraines
• Tempers down the swelling and pain of rheumatoid arthritis
• Improves symptoms of asthma
• Balances the lipid panel to prevent dyslipidemia (i.e., high triglyceride, high LDL, low HDL)

Learn More:

Ginger – Herbal Information: https://www.herbs-info.com/ginger.html
How To Make Natural Ginger Ale: https://herbshealthhappiness.com/how-to-make-natural-ginger-ale/
How To Grow Your Own Ginger: https://herbshealthhappiness.com/how-to-grow-your-own-ginger/

References:

[1] Mashhadi, N. S., Ghiasvand, R., Askari, G., Hariri, M., Darvishi, L., & Mofid, M. R. (2013). Anti-oxidative and anti-inflammatory effects of ginger in health and physical activity: review of current evidence. International journal of preventive medicine, 4(Suppl 1), S36.

[2] Anh, N. H., Kim, S. J., Long, N. P., Min, J. E., Yoon, Y. C., Lee, E. G., … & Yoon, S. J. (2020). Ginger on Human Health: A Comprehensive Systematic Review of 109 Randomized Controlled Trials. Nutrients, 12(1), 157.

21 Uses For Ginger

21 Uses For Ginger
21 Uses For Ginger. Graphic © herbshealthhappiness.com. Ginger image – Pixabay (PD).

Ginger (Zingiber officinale) is an ancient medicinal spice that is valued for its wide range of possible health benefits. It’s consumed in different forms, such as juice, oil, powder, dried, or fresh. Ginger is rich in essential nutrients such as gingerol, magnesium, potassium, niacin, folate, phosphorous, protein, fiber, antioxidants, and anti-inflammatory compounds. [1] These nutrients facilitate several health benefits as shown below.

⦁ Anticancer Potential (Colon cancer, Ovarian cancer, Bowel cancer): Compounds in ginger such as gingerol have been shown to help prevent different types of cancer, including ovarian cancer, colorectal cancer, skin cancer, gastric cancer, and pancreatic cancer. [2][3][4][5][6]

⦁ Alzheimer’s Disease: A study in the Journal of Drug Design, Development and Therapy suggests that ginger could help delay the onset of Alzheimer’s and other neurodegenerative diseases. [7]

⦁ Diabetes: Ginger helps control diabetes and improve insulin resistance in type 2 diabetes. [8]

⦁ Obesity: Studies claim that ginger is a metabolism booster that accelerates weight loss in people with obesity. [9]

⦁ Anti-inflammatory Properties (swelling): Ginger is rich in anti-inflammatory and antioxidant compounds such as salicylate, caffeic acid, curcumin, capsaicin, beta-carotene, and pantothenic acid. [10]

⦁ Cardiovascular Disease: Ginger protects against cardiovascular disease by regulating hypertension, reducing the risk of blood clots, and lowering LDL cholesterol levels. [11]

⦁ Arthritis: The Arthritis Foundation recommends ginger as an alternative remedy to help manage arthritis – thanks to its ability to reduce pain, inflammation, and discomfort. [12]

⦁ Pain Relief (Migraines, toothache): Ginger is as effective as some pharmaceutical alternatives at managing migraines. [13]

⦁ Respiratory Health (cold and flu, cough, sore throat, and stuffy nose): Fresh ginger has antibiotic properties against infections cold, flu, and other respiratory tract infections. [14]

⦁ Digestive Health (heartburn, indigestion, upset stomach, morning sickness): Ancient Chinese medicine used ginger to improve digestive health. [15]

Please note that this content should ever be used as a substitute for direct medical advice from your doctor or other qualified clinicians.

References:

[1] FoodData Central Search Results https://fdc.nal.usda.gov/fdc-app.html#/.

[2] Ginger inhibits cell growth and modulates angiogenic https://doi.org/10.1186/1472-6882-7-44.

[3] 6-Gingerol inhibits osteosarcoma cell proliferation through apoptosis and AMPK activation https://doi.org/10.1007/s13277-014-2723-1.

[4] Nigam N. et al. 2009. [6]-Gingerol induces reactive oxygen species regulated mitochondrial cell death pathway in human epidermoid carcinoma A431 cells. https://www.ncbi.nlm.nih.gov/pubmed/19481070.

[5] Zerumbone inhibits tumor angiogenesis via NF-κB in gastric cancer https://www.spandidos-publications.com/10.3892/or.2013.2842.

[6] Shamoto T. et al. 2014. Zerumbone inhibits angiogenesis by blocking NF-κB activity in pancreatic cancer. https://www.ncbi.nlm.nih.gov/pubmed/24622069.

[7] Faizul Azam. et al. 2014. Ginger components as new leads for the design and development of novel multi-targeted anti-Alzheimer’s drugs: a computational investigation https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4211852/.

[8] Arzati, M. et al. 2014. The Effects of Ginger on Fasting Blood Sugar, Hemoglobin A1c, and Lipid Profiles in Patients with Type 2 Diabetes https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5750786/.

[9] Beneficial effects of ginger Zingiber officinale Roscoe on obesity and metabolic syndrome: a review https://nyaspubs.onlinelibrary.wiley.com/doi/abs/10.1111/nyas.13375.

[10] Chapter 7 The Amazing and Mighty Ginger https://www.ncbi.nlm.nih.gov/books/NBK92775/.

[11] Mazidi M. et al. 2016. The effect of ginger supplementation on serum C-reactive protein, lipid profile and glycaemia: a systematic review and meta-analysis. https://www.ncbi.nlm.nih.gov/pubmed/27806832.

[12] Health Benefits of Ginger for Arthritis https://web.archive.org/web/20190311031028/http://blog.arthritis.org/living-with-arthritis/health-benefits-of-ginger/.

[13] Maghbooli M. et al. 2014. Comparison between the efficacy of ginger and sumatriptan in the ablative treatment of the common migraine. https://www.ncbi.nlm.nih.gov/pubmed/23657930.

[14] Fresh ginger (Zingiber officinale) has anti-viral activity against human respiratory syncytial virus in human respiratory tract cell lines https://doi.org/10.1016/j.jep.2012.10.043.

[15] Ginger in gastrointestinal disorders: A systematic review of clinical trials https://onlinelibrary.wiley.com/doi/full/10.1002/fsn3.807.

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21 Uses For Ginger
Graphic ©herbs-info.com. Image source – Pixabay (PD).

Amazing Uses And Benefits Of Ginger

Amazing Uses And Benefits Of Ginger
Uses And Benefits Of Ginger. Graphic © herbshealthhappiness.com. Photo © AdobeStock (under license)

Ginger Video Transcript:

Ginger is a spice that needs little in the way of introduction, as it is popular worldwide. It was originally a plant that thrived in the southern parts of Asia, where it was used as both a medicine and a spice since ancient times.

Used for:
• Colds
• Antioxidant
• Anti prostate cancer action in lab tests
• Potent antimicrobial against E.Coli
• Arthritis
• Migraines and Hypertension
• Anti-inflammatory
• Anti-nausea
• Scalp tonic
• Antifungal

Perhaps the most common use of ginger root is in the creation of ginger tea, which is simply made with thinly sliced ginger in a cup and boiling water. Add honey and lemon!

When dried, it can be ground into a powder and mixed into foods.

Ginger is sometimes cultivated as a garden or landscape plant due to its colourful flowers and its overall aesthetic appeal.

Ginger is an anti­cancer food: In 2013 scientists discovered that 6­-Shogaol, a major component of ginger, induces apoptosis (cell death) in human leukemia cells both in vitro and in vivo – without side effects!
Source: https://molecular-cancer.biomedcentral.com/articles/10.1186/1476-4598-12-135

Try the classic “ACG” – Apple Carrot Ginger – for a delicious blend that you will feel nourishing your system like water nourishes the roots of a tree. You could also add beet and/or lemon juice to add further nutrition and zing!

A 2014 study showed the effectiveness of ginger supplementation in protecting against oxidative stress – an intervention that is beneficial for obese people.
Source: https://www.sciencedirect.com/science/article/pii/S1728869X14000045

Ginger – Background & Uses

Native to Zanzibar, ginger is the rhizome of the plant Zingiber officinale. [1]

Hot ginger tea has been used for centuries by practitioners of Chinese medicine as a remedy for respiratory ailments, fatigue, and poor circulation. The phytonutrients in ginger replenish nutrients in the body while the high temperature of the liquid and the gingerol activity relieve stomach discomfort, fever, and congestion. [2]

Ginger is believed to be an effective natural remedy for Carpal Tunnel Syndrome. It is considered to be effective in lowering cholesterol and reducing the likelihood of type 2 diabetes. [3] However, these claims have not been verified according to modern science.

As a digestive aid, fever-reducer, expectorant, decongestant, antioxidant, immune-booster, mild painkiller, and antibacterial agent, ginger has been considered a cure-all by practitioners of traditional and alternative medicine. [4]

Ginger – Scientific Studies

Ginger – whether fresh, dried, pickled, preserved, candied, powdered, or crystallized – has been purported to exert a long battery of therapeutic and preventive actions and has been comprehensively studied as regards its efficacy against various pathologic conditions, hence its century-long utility in the management of a number of maladies such as colds, nausea, arthritis, migraine, and hypertension. Several scientific investigations have found evidence with respect to ginger being a potent antioxidant, anticancer, anti-inflammatory, and antinausea agent. [6]

To determine its potential to prevent certain cancers, gingerol–the active component in ginger–has been the focus of clinical trials. Researchers determined that in cases of ovarian cancer, administration of gingerol contributed to cancer-cell death. In cases of ovarian cancer, gingerol was found to reduce inflammation and boost immune function. Researchers have found that Gingerol might protect against colon cancer. [7]

Ginger as antimicrobial: In 2005, an American study compared the antimicrobial activity of garlic, carrot, turmeric, and ginger pastes against Escherichia coli O157:H7 in laboratory buffer and model food system. As revealed by the results of this study, commercial ginger paste exhibited the strongest antimicrobial activity, totally inactivating E. coli O157:H7 in the paste at 3 days at 4°C and 8°C. The commercial ginger paste also showed antimicrobial activity in buffered peptone water at 4°C for 2 weeks. [9] Moreover, the gingerols in ginger root extracts inhibit the growth of Helicobacter pylori CagA+ strains in vitro, as illustrated by another US study in which the methanol extract of ginger rhizome suppressed the growth of all 19 strains in vitro, the minimum inhibitory concentration range being 6.25–50 μg/mL. [8]

Ginger as anti-inflammatory, pain reliever & anti-arthritic: Ginger has long been considered as an effective anti-inflammatory agent that suppresses prostaglandin synthesis through the inhibition of both cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2). [19] However, the results from the study of van Breemen, Tao, and Li (2011) reveal slightly otherwise and contend that purified 10-gingerol, 8-shogaol, and 10-shogaol suppress COX-2 – but not COX-1 – with IC50 values of 32μM, 17.5μM, and 7.5μM. [10] Ginger’s anti-inflammatory mechanism of action is very similar to that of today’s non-steroidal anti-inflammatory drugs (NSAIDs), but ginger goes one step ahead of NSAIDs in being able to suppress leukotriene biosynthesis also by inhibiting 5-lipoxygenase. [9]

The pungent constituent of ginger, 6-gingerol, possesses analgesic and anti-inflammatory effects, as proven by Young et al. (2005) in their study, and thus contributes to ginger’s anti-inflammatory action. [11] Another important anti-inflammatory mechanism of ginger is its inhibitory influence on the induction of many genes associated with the inflammatory response, such as those encoding cytokines, chemokines, and cyclooxygenase-2. [9] Ramadan, Al-Kahtani, and El-Sayed (2011) had also demonstrated the anti-inflammatory action of ginger, significantly inhibiting the incidence and severity of arthritis by decreasing the production of proinflammatory cytokines and activating the antioxidant defense system at a dose of 200 mg/kg body weight. [12]

Ginger as antioxidant and anti-cancer agent: A number of studies have reported the chemopreventive and antineoplastic effects of ginger, implicating its effectiveness in diverse biological actions, including free radical scavenging, influence on antioxidant pathways, alteration of gene expressions, and induction of apoptosis which in turn decrease tumor initiation, promotion, and progression. [13] In 2012, a US study in the British Journal of Nutrition had determined that daily ginger extract consumption (at a dose of 100 mg/kg body weight) inhibits the growth and progression of human prostate cancer cell line (PC-3) xenografts by 56% but spares normal rapidly dividing tissues, such as gut and bone marrow, from any growth-inhibitory and death-inductory effects. [14]

6-Gingerol induces cell death in human promyelocytic leukemia (HL-60) cells through its mediating activities on reactive oxygen species such as hydrogen peroxide and the superoxide anion and causes DNA fragmentation and inhibits Bcl-2 expression in HL-60 cells. [15] 6-Shogaol and 6-gingerol possibly possess anti-invasive properties against hepatoma cells through the regulation of MMP-9 and TIMP-1. Furthermore, 6-shogaol could further regulate urokinase-type plasminogen activity. [16]

Old Drawing Of Ginger Plant

Ginger

Other names for Ginger, past or present:

English – Gingifere
Latin – Zingiber officinale
Greek – Zingiberis
French – Gingembre
German – Ingwer
Spanish – Jenbibre
Italian – Zenzero
Chinese (Mandarin) – Jiang; Sheng jiang
Japanese – Shoga, Jinja, Myoga
Korean – Kon-gang, Geon-gang, Jinjeo, Chinjo, Saenggang
Indonesian – Aliah, Jae, Lia
Hindi – Adrak, Adrakh; Sonth, Saunth

References:

[1] Ginger. Wikipedia.

[2] Balch, Phyllis A. Prescription for Herbal Healing: An Easy-to-Use A-Z Reference to Hundreds of
Common Disorders and Their Herbal Remedies. 2002. Penguin Putnam NY.

[3] Peirce, Andrea. The American Pharmaceutical Association practical guide to natural medicines 1999. Stonesong Press, Inc. New York.

[4] Khalsa, Karta Purkh Singh and Michael Tierra. 2008. The Way of Ayurvedic Herbs: The Most Complete Guide to Natural Healing and Health with Traditional Ayurvedic Herbalism. Lotus Press: Twin Lakes, WI.

[5] Peirce, Andrea. The American Pharmaceutical Association practical guide to natural medicines 1999. Stonesong Press, Inc. New York.

[6] Bode A. M. & Zigang D. (2011). The Amazing And Mighty Ginger. In Benzie I. F. F. & Wachtel-Galor S. (Ed.), Herbal medicine: Biomolecular and clinical aspects (2nd ed.). Boca Raton, FL: CRC Press. Retrieved 4 March 2013 from http://www.ncbi.nlm.nih.gov/books/NBK92775/

[7] Gupta S. & Ravishankar S. (2005). A comparison of the antimicrobial activity of garlic, ginger, carrot, and turmeric pastes against Escherichia coli O157:H7 in laboratory buffer and ground beef. Foodborne Pathogens and Disease, 2(4): 330–340. Retrieved 4 March 2013 from http://www.ncbi.nlm.nih.gov/pubmed/16366855

[8] Mahady G. B., Pendland S. L., Yun G. S., Lu Z. Z., Stoia A. (2003). Ginger (Zingiber officinale Roscoe) and the gingerols inhibit the growth of Cag A+
strains of Helicobacter pylori. Anticancer Research, 23(5A): 3699–3702. Retrieved 4 March 2013 from http://www.ncbi.nlm.nih.gov/pubmed/14666666

[9] Grzanna R., Lindmark L., & Frondoza C. G. (2005). Ginger – an herbal medicinal product with broad anti-inflammatory actions. Journal of Medicinal Food, 8(2): 125–132. Retrieved 4 March 2013 from http://www.ncbi.nlm.nih.gov/pubmed/16117603

[10] van Breemen R. B., Tao Y., & Li W. (2011). Cyclooxygenase-2 inhibitors in ginger (Zingiber officinale). Fitoterapia, 82(1): 38–43. doi:
10.1016/j.fitote.2010.09.004. Retrieved 4 March 2013 from http://www.ncbi.nlm.nih.gov/pubmed/20837112

[11] Young H. Y., Luo Y. L., Cheng H. Y., Hsieh W. C., Liao J. C., & Peng W. H. (2005). Analgesic and anti-inflammatory activities of [6]-gingerol. Journal of Ethnopharmacology, 96(1–2): 207–210. Retrieved 4 March 2013 from http://www.ncbi.nlm.nih.gov/pubmed/15588672

[12] Ramadan G., Al-Kahtani M. A., & El-Sayed W. M. (2011). Anti-inflammatory and anti-oxidant properties of Curcuma longa (turmeric) versus Zingiber officinale (ginger) rhizomes in rat adjuvant-induced arthritis. Inflammation, 34(4): 291–301. doi: 10.1007/s10753-010-9278-0. Retrieved 4 March 2013 from http://www.ncbi.nlm.nih.gov/pubmed/21120596

[13] Baliga M. S. et al. (2011). Update on the chemopreventive effects of ginger and its phytochemicals. Critical Reviews in Food Science and Nutrition, 51(6):
499–523. doi: 10.1080/10408391003698669. Retrieved 4 March 2013 from http://www.ncbi.nlm.nih.gov/pubmed/21929329

[14] Karna P. et al. (2012). Benefits of whole ginger extract in prostate cancer. British Journal of Nutrition, 107(4): 473–484. doi: 10.1017/S0007114511003308. Retrieved 4 March 2013 from http://www.ncbi.nlm.nih.gov/pubmed/21849094

[15] Wang C. C., Chen L. G., Lee L. T., & Yang L. L. (2003). Effects of 6-gingerol, an antioxidant from ginger, on inducing apoptosis in human leukemic HL-60 cells. In Vivo, 17(6): 641–645. Retrieved 4 March 2013 from http://www.ncbi.nlm.nih.gov/pubmed/14758732

[16] Weng C. J., Wu C. F., Huang H. W., Ho C. T., Yen G. C. (2010). Anti-invasion effects of 6-shogaol and 6-gingerol, two active components in ginger, on human hepatocarcinoma cells. Molecular Nutrition & Food Research, 54(11): 1618–1627. doi: 10.1002/mnfr.201000108. Retrieved 4 March 2013 from http://www.ncbi.nlm.nih.gov/pubmed/20521273

Main article: Kelsey Wambold. Scientific Studies report: Dan Ablir © herbshealthhappiness.com

Uses And Benefits Of Ginger
Uses And Benefits Of Ginger
Graphic © herbshealthhappiness.com. Photo © Shutterstock (under license)